Principal NGS Automation Architect

A bout our Company: Universal D X , Inc . is an international Company with a highly experienced team focused on cracking cancer’s code. Through our multi-omics and bioinformatics models, we have figured out how to read the disease’s signals in blood with high accuracy to detect cancer in its earliest stages.

Starting with a colorectal cancer screening liquid biopsy test , we are building a multi-cancer platform that can identify the unique DNA regions associated with different types of cancers. The Opportunity: Universal DX is seeking an experienced Principal N GS Automation Architect to lead the design, development, implementation, and continuous improvement of automated next-generation sequencing (NGS) laboratory workflows supporting in vitro diagnostic (IVD) assay development, analytical validation, and commercialization.

Requirements

. The successful candidate will possess deep, hands-on liquid-handling method development and systems-level architecture expertise for NGS workflows, a strong understanding of molecular assay

, and experience developing robust, scalable, and compliant automation suitable for clinical and IVD environments . You will be part of a team that is passionate about developing novel diagnostic tests for the early detection of cancers. As part of the team, you will be in a Company that aims more than to become one of the leaders in the industry.

We want to have a huge positive impact on society by achieving the ambitious purpose of “making cancer a curable disease by detecting it earlier”. How you’ll contribute: Automation Architecture and Development Design the end-to-end automation architecture for NGS sample preparation and in-process quality control workflows. Evaluate, select, and implement laboratory automation platforms, integrated devices, labware, consumables, and supporting technologies.

Develop automation strategies that maximize throughput, reproducibility, robustness, and operational efficiency. Develop and optimize liquid handling methods including deck layouts, labware definitions, liquid classes and pipetting parameters, mixing, temperature control, and error-recovery strategies, to maintain assay performance while minimizing carryover, variability , and failure modes. Assay Integration Serve as the primary technical interface between assay development scientists and automation engineers.

design inputs, critical process parameters, and control strategies into automated workflows while maintaining analytical performance.

for IVD products. Generate and review documentation . D.

in Molecular Biology, Biomedical Engineering, Bioengineering, Biotechnology, Chemical Engineering, Automation Engineering, or a related scientific or engineering discipline. 8+ years of experience developing and deploying automated laboratory workflows for molecular diagnostics, genomics, or biotechnology. Experience supporting automation of DNA methylation assays and liquid biopsy workflows is preferred.

Demonstrated experience automating NGS workflows including library preparation and target enrichment. , Hamilton, Tecan, Beckman Coulter, or similar).

into automated laboratory processes. Knowledge of NGS technologies and molecular biology techniques.