About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts.

com/ Position Purpose: The Director, Corporate Strategy partners closely with leaders across the organization to drive enterprise-wide strategic planning, governance processes, organizational planning, and high-priority cross-functional initiatives. This position will report into the VP, Corporate Strategy and Chief of Staff and requires a highly collaborative leader with strong biotech/pharmaceutical experience, exceptional communication and organizational skills, and the ability to navigate complex, matrixed environments.

Key Responsibilities

: Serve as strategic thought partner and operational extension of the VP, Corporate Strategy and Chief of Staff. Partner cross-functionally with leaders and stakeholders to support the company’s annual strategic planning process Lead the annual corporate and departmental goal-setting process by working with functional leaders to translate corporate strategy into measurable business goals and monitoring progress against goals throughout the year. Manage Board meeting operations, including agenda development, preparation of materials, documentation of key decisions and action items, and coordination of follow-up activities.

Prepare executive-level materials for Board meetings, leadership reviews, and governance forums Support the design, implementation, and continuous improvement of the company's governance framework, operating model, and decision-making processes. Lead high-impact, cross-functional strategic initiatives, applying analytical and data-driven approaches to evaluate complex business questions, develop recommendations, and drive execution. Drive cross-functional action tracking and follow-through for executive leadership to ensure alignment and timely execution.

Build strong relationships across senior leadership and act as a connector between functions Foster a culture of collaboration, accountability, and patient-centricity Required Skills & Experience: 10+ years of experience in consulting, investment banking, private equity, or corporate strategy Bachelor’s degree required; Master’s degree in business preferred Strong experience in strategy consulting or in-house strategy Strong familiarity with the pharmaceutical/biotech industry and drug development landscape. Highly collaborative team player with the ability to work effectively across all departments to build trusted partnerships with various stakeholders Excellent attention to detail and oral/written communication Strong financial, analytical and problem-solving skills with a proven ability to apply these skills in complex situations with competing priorities Highly self-motivated with demonstrated agility to multitask, manage time, handle uncertainty, and work under pressure with limited oversight. Location(s): Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026.

This position is a hybrid position currently based in Bedford and will later be based in Waltham.