About Summit: Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality.

Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence. Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology.

Summit has multiple global Phase 3 clinical studies, including: Non-small Cell Lung Cancer (NSCLC) HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI. HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC. HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC) HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy. Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Location : Princeton, NJ ONSITE Overview of Role: We are seeking a highly motivated, solutions-oriented Director, Clinical Supply Chain IRT to lead the development, implementation, and continuous improvement of IRT standards across clinical development programs.

Requirements

into clear standards, robust processes, and effective system solutions. The Director, Clinical Supply Chain IRT will serve as the subject matter expert and process owner for IRT standards and related ways of working. The role will partner closely with Clinical Supply Chain, Clinical Operations, Quality, IT, external vendors, and study teams to deliver fit-for-purpose IRT solutions that support efficient study start-up, reliable execution, compliant change management, and scalable clinical supply operations.

Responsibilities

: Lead development and process improvement activities within and across teams, including knowledge-sharing sessions, training forums, and targeted information sessions Provide expert consultancy to internal and external stakeholders on study-specific IRT solutions, process development, program strategy, and practical options to meet evolving program needs Act as process owner for IRT processes and sub-processes, ensuring they remain clear, compliant, efficient, and scalable Set the standard for excellence in IRT setup, change management, and cross-functional delivery, while modelling the values, behaviors, and performance expectations required in a dynamic biotech environment All other duties as assigned Experience, Education and Specialized Knowledge and Skills: Bachelor’s degree in life sciences, supply chain, pharmacy, or a related discipline; advanced degree preferred Significant experience (10+ years) in Clinical Supply Chain, Clinical Operations, IRT/RTSM, or a closely related clinical development functio