Imagine if you had the skills, knowledge, and teammates to both understand the root of the world’s most pressing problems and build the technologies and companies best positioned to solve them. RA Capital has done exactly that for more than two decades, backing bold ideas in medicines to further human health and now expanding into Planetary Health to improve how efficiently we utilize the world’s precious resources. RA Capital is among the leading providers of capital and services to the most promising innovators in the world.

We invest flexibly—seed to IPO and beyond, anywhere in the world—with $10 B+ under management and a culture that prizes curiosity, rigor, and collaborative debate. We are investors who not only fund companies but get elbow deep in building them. From helping them recruit talent to helping them recruit patients for their studies to helping match them to strategic partners and even going to Washington to win reforms, RA Capital’s large team has people with nearly every relevant expertise one might need to turn an idea into a cure that actually helps people.

If you live for first-principles problem-solving with great colleagues, thrive on complexity, and want to do meaningful work that ripples across industries and ecosystems, you’ll feel at home at RA Capital. Here, questions are welcomed, ideas are tested, and victories are shared. Even our lawyers are creative and engaging.

And don’t get us started on our compliance team’s wicked sense of humor; nothing about what we do is boring. Are you ready to bring your creativity, discipline and collaborative spirit to help us invent the future? Join us and you’ll collaborate daily with investors, founders, physicians, biologists, engineers, economists, and reform advocates who think in systems and act with urgency.

Join us to invent a happier, healthier, more productive future - and have fun doing it. RA Capital Management is seeking a highly motivated and detail-oriented Trade Operations Analyst to join its Operations team. Reporting directly to the Director of Operations, this role will support all aspects of trade and treasury operations across the firm’s hedge fund, separately managed accounts, and commitment-based venture funds.

The role is execution-oriented and requires strong analytical capabilities, attention to detail, and comfort managing multiple priorities in a fast-paced environment. This position will focus on trade support, reconciliations, treasury management, middle office operations, regulatory reporting support, and operational process improvement, while partnering closely with internal teams and external counterparties to ensure accuracy, efficiency, and scalability of operational workflows.

Key Responsibilities

Review daily cash and position reconciliations across multiple accounts and counterparties Provide trade support, including trade booking, symbol setup, and maintenance Maintain and enhance security master data, including user-defined fields and operational reference data Resolve administrator, prime broker, and trader inquiries related to trade breaks, settlement issues, lifecycle events, and live or historical P&L questions Assist in managing relationships with fund administrators, middle office providers, and other external operational partners Support filings related to daily trading activity, including 13G/D and Section 16 filings Assist with regulatory reporting

Requirements

, including Form PF, 13F, and related filings Support oversight of operational, legal, and compliance workflows, including best execution, valuation policies, and trading documentation

Manage treasury-related functions, including cash forecasting, wire processing, and capital activity monitoring Review and optimize leverage usage across prime broker relationships Monitor stock borrow costs and financing activity across counterparties Process wires accurately and in a timely manner while adhering to internal controls and operational procedures Iden