Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

We are seeking a highly motivated and innovative researcher to join our LNP Formulation team. This role is central to our mission of advancing next-generation gene editing therapies. You will play a pivotal role in the formulation, characterization, and optimization of Lipid Nanoparticle (LNP) delivery systems, transitioning breakthrough AI-designed gene editors from the bench to in vivo applications.

The ideal candidate will have extensive hands-on experience with LNP formulation, process development and LNP characterization. This is an excellent opportunity to work cross-functionally with a diverse team of experts across AI and machine learning, protein design, cell biology, and gene editing.

Responsibilities

Execute the formulation of LNPs encapsulating diverse gene editing payloads (mRNA, sgRNA) for in vitro validation and in vivo preclinical studies. g.

Qualifications

Research Associate II: BS with 2+ years of relevant industry experience.

What We Offer

High-growth opportunity with meaningful impact on the future of protein design Competitive

Compensation

package with equity participation 401(k) with a strong employer match Comprehensive

Benefits

including health/dental/vision insurance Generous PTO policy and commitment to work-life balance Professional development opportunities in a cutting-edge field at the intersection of AI and biology Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace.

Research Associate II - Senior Research Associate II, LNP Formulation & Drug Delivery