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Dispatch Bio — Philadelphia Pennsylvania
About us: Our purpose at Dispatch is to help create a world where all cancer patients can be cured. We’re humbled by the opportunity to work together as a team on some of the most pressing medical challenges of our time. To achieve our purpose, we are dedicated to engineering a universal treatment across solid tumors.
We’re committed to the development of novel therapies, leveraging first-in-class technologies in viral vectors, universal targets, and novel cytokine biology. Our therapeutic approach has the potential to enable us to treat significant numbers of cancer patients and make a real and lasting impact on the world. Our company was founded on pioneering work carried out in the laboratories of Dr.
Carl June (University of Pennsylvania), Dr. Kole Roybal (University of California, San Francisco), Dr. Christopher Garcia (Stanford University) and Dr.
Andy Minn (Memorial Sloan Kettering Cancer Center). At our company, you would become one of our early team members— not only playing a role in meeting our ambitious mission but also building our thriving culture. We are determined to deliver with urgency to discover new solutions and we always stay dedicated to scientific rigor; we have an ownership mindset because each and every one of us is integral to our success.
Collaboration is core for us because we believe that by bringing people together with diverse perspectives, we make a stronger whole. And, we show we care about our work and each other by sharing feedback - ultimately in service of our vision to empower people to continue forward with their lives – cancer free. The role: Reporting to the Director, Upstream Process Development, the (Associate) Scientist will contribute to upstream viral process development to bring the company’s pipeline of T cell and viral vector-based products to the clinic.
Responsibilities
will include, but are not limited to, performing the day-to-day activities of the viral process development lab, building the company’s viral manufacturing capabilities, and executing experiments to support viral process development/characterization. This role will collaborate significantly with research and analytical development teams.
Key Responsibilities
: Contribute to the setup and organization of the company’s vector process development capabilities. Perform day-to-day activities in the vector process development lab including maintaining equipment, ordering materials, managing inventory, and preparing buffers and process aids. ).
Develop bench scale suspension culture processes for viral vector generation within shake flasks and bioreactors. Design and execute experiments to support process characterization, and process transfer activities between the research team, TechOps, and external partners. Provide experimental execution, data review and analysis, and maintenance of accurate and detailed lab notebooks.
Author and review technical documents, including but not limited to batch records, SOPs, development reports and process specific sections of regulatory documents.