Clinical Project Director/Associate Director

About ProteinQure At ProteinQure, we have built the best computational platform for peptides that target extracellular targets. Our mission is to help to create a world where drugs are engineered, not discovered. We work on treatments for cancer and other indications while also partnering with industry leaders in drug discovery to generate novel therapeutics outside of the conventional chemical space.

Our technology combines computational biophysical models with statistical and machine learning approaches to enable us to search across vast spaces of protein therapeutics. We have worked with three of the top 25 pharma companies and have validated our tools on multiple targets. We also have multiple internal programs, the most advanced is a First-in-Class peptide drug conjugate for TNBC, which is in a Phase 1 clinical trial including the best sites in North America.

A second clinical program is expected within 3 years. Our other internal programs focus on using peptides as delivery vehicle for therapeutic payloads such as radioisotopes and siRNA. ProteinQure is a Series A-stage company and has raised its Series A round of USD $10M.

We are looking for a Director or Associate Director of Clinical Development to run the clinical operations for assets in clinical studies.

Compensation

Range: $120,000 to 170,000 CAD annually, based on skills,

Qualifications

, and relevant experience. The Director (D)/Associate Director (AD) Clinical Development is responsible for leading various functions to support clinical trials with ProteinQure’s compounds as well as supporting the translation and development of lead compounds towards the clinic. Within the Translation group, this position reports directly to the VP of Translation and Development, and will work closely with the CEO and Chief Medical Officer as well as Exp Bio, Regulatory, Quality, CMC and Program Management functions to ensure smooth information flow between departments.

The D/AD will primarily be responsible for the design and execution of clinical trials at ProteinQure and will present or oversee the presentation of progress and data to members of the Management Team at ProteinQure. The successful candidate must have the ability to multitask and function effectively in a fast-paced environment. They must be able to develop strong interpersonal relationships and work with internal and external stakeholders to effectively meet the temporal, quality and financial goals for any clinical studies.

A key part of the job is managing external collaborations and contract organizations. The D/AD may be asked to manage internal personnel as appropriate but that cannot be guaranteed. This job posting is to fill an existing position.

Artificial intelligence may be used to assist in the initial screening of resumes for this position. This process is supervised by a human, and hiring decisions are not made solely by artificial intelligence.

Key Responsibilities

include: Accountable for the delivery of assigned clinical trial tasks including budgets, timelines, implementation, operations and resource management with a focus on quality, including making recommendations and decisions regarding operational strategies to support trials and/or program objectives. For trials using external CROs, lead the implementation of procedures to ensure harmonization of internal and external efforts and oversight of the CRO, including the establishment of quality metrics to assure proper performance against the contract. Manage and co-ordinate efforts of cross-functional project teams to support milestone achievement and to manage trial/program issues and obstacles.