Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. com/ , and follow us on X , LinkedIn and Facebook . Role Summary: The Senior Director, Program Management (PM) is a critical role within the cross-functional development team responsible for facilitating and driving execution across the wide spectrum of activities required for successful development of one or more molecules.

The PM partners closely with the Program Team Leader (PTL) and functional subject matter experts to ensure that plans are in place with appropriate detail and risk awareness to assure successful achievement of the goals of the development team. The PM ensures integration of these detailed functional plans into a holistic, cohesive, and comprehensive program plan that achieves the strategic goals of the development program. Given the inherent uncertainty associated with drug development in rare disorders, the PM maintains an agile mindset in order to effectively incorporate and react to emerging data and course correct as conditions dictate.

Working in close partnership with the PTL, the PM effectively frames and facilitates discussions with team members and external experts to elicit clear recommendations and decisions by fully engaging with team members to consider multiple options with a focus on impact on quality, time, and cost. Their influence and engagement skills allow them to work with a highly motivated team and manage stakeholders at all levels of the company. This role is based in Waltham, MA without the possibility of being a remote role.

Responsibilities

Include : Lead the operations of one or more high performing cross-functional teams, with focus on both the “what”, such as priorities, goal achievement, and resources, and the “how” of maintaining a challenging, collaborative, and sustainable team environment Partner with the PTL to identify short, medium, and long-term team priorities and propose path to address Drive execution of the established and aligned Program vision and strategy for bringing a life-changing medicine to patients in need Facilitate creation & maintenance of core program strategy documents including Target Product Profile (TPP), Clinical Development Plan, Regulatory Strategy, and Supply Strategy in collaboration with cross-functional representatives Ensure that non-clinical, clinical, regulatory, and commercialization strategies and plans are aligned with the TPP and the overall Program Strategy Inspire development of an efficient plan to achieve development and commercialization strategy, optimizing for quality, speed and cost Ensure that program decisions are made in a timely, clear and efficient manner through interactions with the PTL, Program Team members, governance forums and other key stakeholders Accountable for creation and maintenance of detailed cross-functional plans and effective visual summaries thereof to instill awareness, build accountability and facilitate achievement Maintain clear and open communication with Program Team, Dyne Senior Leadership, and other stakeholders regarding program status, priorities, risks and needs, and facilitate appropriate strategic decision-making Partner with Head of Program Management to evolve Program Management discipline to meet needs of a growing organization that intends to launch a portfolio of disease products Keep abreast of emerging developments regarding research and development in