About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts.

com/ Position Purpose: Stoke Therapeutics is seeking a highly motivated Patent Agent to join its Intellectual Property team. This individual will report to the Head of Intellectual Property and will play an important role in protecting Stoke's innovations and supporting the company's intellectual property strategy. S.

and foreign patent prosecution, patent application drafting, patentability and freedom-to-operate analyses, competitive intelligence, docket management, and internal IP education. This role is based in Bedford/Waltham, MA three days a week and is not available for remote applicants. It is an excellent opportunity for a patent professional with a strong technical background in chemistry, biochemistry, molecular biology, or a related life sciences field, and with experience supporting biotech or pharmaceutical patent portfolios.

Familiarity with antisense oligonucleotides, RNAi, mRNA technologies, oligonucleotide chemistry, nucleic acid therapeutics, or related RNA-based therapeutic platforms is highly desirable.

Key Responsibilities

S. Patent and Trademark Office actions and coordinate responses to foreign office actions with outside counsel and foreign associates. Draft and assist with the preparation of provisional, non-provisional, PCT, continuation, divisional, and foreign patent applications.

Support global patent prosecution strategy for Stoke's research and development programs. Work with outside counsel to ensure high-quality, strategically aligned patent filings and prosecution positions. Review and analyze prior art, office actions, search reports, written opinions, and examination reports.

Maintain and update patent docket records, portfolio records, invention disclosure records, and related IP documentation. Invention Capture and Portfolio Development Partner with scientists and technical teams to identify patentable inventions and develop appropriate patent protection strategies. Review invention disclosures, research updates, publications, posters, abstracts, presentations, and manuscripts for potential IP implications.

Develop and deliver IP trainings for internal scientists and R&D teams, including training on invention disclosure practices, publication review, confidentiality, patent filing strategy, and good IP hygiene. Help maintain and develop a global patent portfolio aligned with Stoke's scientific, clinical, and business objectives. Patentability, FTO, and Competitive Intelligence Conduct patentability, landscape, freedom-to-operate, validity, and competitive intelligence searches.

Monitor competitor patent filings, publications, clinical developments, and relevant patent office proceedings. Prepare summaries and analyses of third-party patent positions and competitive IP developments.